Jose Mourinho expects to be without Toby Alderweireld for some time as the center-back suffered an injury in Tottenham’s 2-0 win over Man City.
The Belgium international was sent off nine minutes from time due to an apparent adductor injury in the victory at Tottenham Hotspur Stadium.
His absence will be felt with games against Chelsea, Arsenal, Liverpool and Leicester next month for Spurs.
“It’s bad, it’s bad. It’s a muscle injury, ”Mourinho said. “The dimension of course that we don’t know, you have to wait, but it’s a difficult injury for sure.
“In the Premier League we have three central defenders, in the Europa League we don’t have Joe Rodon, we only have two, but that’s how it is.
“We have no one to blame. He played in the international games the team needed to win to qualify for the last four (of the Nations League). With us it plays so well that we decided to play it rather than put it down.
“There’s no one to blame, just to recover as quickly as possible.”
In October, Rodon made his first appearance at Tottenham Hotspur Stadium when he was presented in place of Alderweireld and could now be in line for his full debut at Chelsea next Sunday.
The young Welsh center-back has signed for Spurs after registering their squad for the Europa League, which means Davinson Sanchez is set to make his home Group J game against Ludogorets on Thursday.
Another alternative for Mourinho in the future is academy graduate Japhet Tanganga, who is strengthening his form after a stop-start campaign, while left-back Ben Davies has regularly played more centrally for Wales.