Saints vs. Cardinals odds, line, spread: Thursday Night Football picks, NFL predictions from advanced model

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The New Orleans Saints (2-4) travel to State Farm Stadium to take on the Arizona Cardinals (2-4) on Thursday Night Football. Both clubs have suffered defeats in their last encounters. Last week, New Orleans lost to the Cincinnati Bengals 30-26. Meanwhile, the Cardinals lost back-to-back games and lost 19-9 to the Seattle Seahawks last Sunday. The Cardinals are 3-3 ATS this season, while the Saints are 2-4.

Kickoff is scheduled for 8:15 p.m. ET from State Farm Stadium. Arizona is favored by two points in Caesars Sportsbook’s latest Saints vs. Cardinals odds, and the over/under is 44.5. Before making Cardinals vs. Saints picks, you need to see NFL predictions and SportsLine’s computer simulation model betting tips.

The model, which simulates every NFL game 10,000 times, has grown nearly $7,000 for players to $100 on top NFL picks since its inception. The model enters Week 7 of the 2022 NFL season on an incredible 146-107 run on NFL’s top picks that dates back to the 2017 season.

The model has also ranked in the top 10 on NFLPickWatch four of the last six years on NFL direct picks and has beaten more than 94% of CBS Sports Football Pick’em players four times during that time. Anyone who followed him is upstairs.

Now the model has set its sights on Saints vs Cardinals and has just locked in its TNF picks and predictions. You can visit SportsLine now to see the model choices. Here are the NFL odds and betting lines for Cardinals vs. Saints:

  • Saints vs. Cardinals spread: Arizona -2
  • Saints vs. Cardinals over/under: 44.5 points
  • Silver line Saints vs Cardinals: New Orleans +110, Arizona -130
  • NO: Saints are 4-1 ATS in their last five games after a straight loss
  • ARI: Under bets are 5-0 in Cardinals’ last five games
  • Saints vs. Cardinals Picks: See the picks here

Featured game | Arizona Cardinals vs. New Orleans Saints

Why Cardinals Can Cover

The Cardinals played very strong defensively. This group has the speed to fly around the court and make plays on the ball. Arizona is 12th in the league in total yards allowed (337.3) and seventh in rushing yards allowed (103.8). Security Budda Baker is an athletic and explosive difference maker. Baker is fast and can produce big hits. The Washington product was a tackle machine, leading the team in total saves (45) with a forced fumble. In his last contest, he recorded six total tackles.

Linebacker Zaven Collins has a superb combination of size and speed. Collins has plenty of sparkle and length for shallow players. The Tulsa product is second on the team in total tackles (41), tied for first in the TFL (four) and has two sacks. See which team to support here.

Why saints can cover

Running back Alvin Kamara has been a multi-dimensional weapon for New Orleans. Kamara is a savvy receiver out of the backfield with precise running and sticky hands. The five-time Pro Bowler has strong vision and superb contact balance. He has 66 carries for 302 yards, or 4.6 yards per carry. Kamara also had 17 passes for 139 receiving yards. Kamara has recorded consecutive games with over 100 yards from scrimmage.

Taysom Hill is another versatile piece within the attack. Hill can line up at quarterback in some rosters while still being able to play short end. The BYU product is often touted as a red zone running back with the ability to beat defenders with his speed. Hill has 26 carries for 267 yards and a team-best five rushing scores. In Week 4, he rushed for 112 yards with three touchdowns. See which team to support here.

How to Make Saints vs. Cardinals Choices

SportsLine’s model looks at the total, calling for a combined 49 points. It also indicates that one side of the spread cashes in more than 50% of the simulations. You can only get the model’s TNF picks from SportsLine.

So who wins Cardinals vs. Saints on Thursday Night Football? And which side of the gap hits more than 50% of the time? Visit SportsLine now to see which side of the Cardinals vs. Saints spread, all from the forward model that has risen nearly $7,000 on his NFL picks since 2017, and find out.



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