Baker Mayfield and the Carolina Panthers (1-2) take on Kyler Murray of the Arizona Cardinals (1-2) on Sunday at Bank of America Stadium in Charlotte. The Panthers are coming off an impressive 22-14 victory over the New Orleans Saints in Week 3, while the Cardinals are hoping to rebound from a 20-12 loss to the defending Super Bowl champion Los Rams. Angeles. The Panthers and Cardinals have met 19 times, with Carolina holding a 14-5 advantage. Carolina All-Pro running back Christian McCaffrey (thigh) remains questionable for this game.
Kickoff is at 4:05 p.m. ET. Carolina is 1-point favorite in Caesars Sportsbook’s latest Panthers vs. Cardinals odds, and the over/under is set at 43.5. Before you make Cardinals vs. Panthers picks, you’ll want to see NFL predictions and SportsLine’s computer simulation model betting tips.
The model, which simulates every NFL game 10,000 times, has grown nearly $7,000 for players to $100 on top NFL picks since its inception. The model enters Week 4 of the 2022 NFL season on an incredible 139-103 run on the NFL’s top picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on NFL Direct Picks and has beaten over 94% of CBS Sports Football Pick’em players four times during that time. Anyone who followed him is upstairs.
Now, the model has set his sights on the Panthers vs. Cardinals and has just locked in his picks and NFL Week 4 predictions. You can head over to SportsLine now to see the model choices. Here are several NFL odds and betting lines for Cardinals vs. Panthers:
- Spread Panthers vs. Cardinals: Panthers -1
- Panthers vs. Cardinals over/under: 43.5 points
- Panthers pick vs. Cardinals: See picks here
Featured game | Carolina Panthers vs. Arizona Cardinals
What you need to know about the Panthers
The Panthers beat the New Orleans Saints 22-14 last Sunday. Carolina WR Laviska Shenault Jr. filled the stat sheet, catching two passes for a touchdown and 90 yards. Near the top of the highlight reel was Baker Mayfield’s 67-yard TD bomb against Shenault Jr. in the fourth quarter.
The Panthers could do without McCaffrey, which would be a blow to their offense. The former Stanford standout is coming off back-to-back 100 rushing yards and ranks fifth in the league in total rushing yards. If he’s unable to play, Carolina will need Mayfield to produce at a level he hasn’t reached in his three starts with the franchise.
What you need to know about cardinals
Meanwhile, Arizona fell short against the Los Angeles Rams last Sunday, losing 20-12. One thing that worked against Arizona was the running game. Top running back James Conner rushed for just 39 yards on 13 carries.
The Cardinals have made it clear they are looking to involve Conner more to take some of the pressure off Murray. Arizona rushed for a modest 316 yards in three games, but 65 of those yards came from Murray. Arizona is shorthanded at wide receiver with AJ Green (knee, out), Rondale Moore (hamstring, questionable) and Marquise Brown (foot, questionable) all struggling with injuries, and DeAndre Hopkins suspended for three more games.
How to make Panthers vs. Cardinals picks
The model has simulated Panthers against Cardinals 10,000 times and the results are there. The model looks at the point total, and it also indicates that one side of the gap has all the value. You can only see the model choice on SportsLine.
So who wins the Cardinals against the Panthers? And which side of the spread has all the value? Visit SportsLine now to find out which side of the Panthers vs. Cardinals split you should be on everywhere, all from the model on a 139-103 roll on his top-rated NFL picks, and find out.
