The Los Angeles Rams have never had a losing record at any time during head coach Sean McVay’s tenure, but that streak will be put to the test when the defending champions host the Buffalo Bills in the game. 2022 NFL kickoff Thursday. Los Angeles will unveil its Super Bowl banner from last season before taking on this year’s Super Bowl favorite, setting up plenty of potentially winning NFL DFS rosters. Buffalo has perhaps the best quarterback in the NFL in Josh Allen, while Los Angeles wide receiver Cooper Kupp is fresh off a historic campaign. There are also defensive stars on both rosters, which might make NFL DFS picks a challenge without a little NFL DFS advice. Before you set your NFL DFS lineups for Rams vs Bills on sites like DraftKings and FanDuel, be sure to check out SportsLine Fantasy daily expert Mike McClure’s NFL DFS tips, strategy and stacks.
McClure is a legendary DFS professional player with over $2 million in career earnings. His methodology has led to huge wins on FanDuel and DraftKings. He won two high-stakes tournaments on FanDuel in 2020 and recorded two top 10 finishes in tournaments with over 130,000 participants on DraftKings. His rosters have also finished in the top 1% in over a dozen other tournaments.
It uses a powerful prediction model that simulates every instant NFL action, taking into account factors such as games, statistical trends, and injuries. This allows him to find the best DFS values which he only shares with SportsLine members.
Now, McClure has turned his attention to Bills vs. Rams in the NFL Opener and has locked in his top fantasy football daily picks. You can only see them by going to SportsLine.
Top NFL DFS picks for Rams vs Bills
One of McClure’s top NFL DFS picks for the NFL Kickoff Game is Rams wide receiver Cooper Kupp. He had one of the best offensive seasons in league history last year, leading the NFL in receptions (145), receiving yards (1,947) and receiving touchdowns (16). Kupp added icing on the cake when he had eight catches for 92 yards and two touchdowns against Cincinnati en route to a Super Bowl MVP.
He signed a three-year, $80 million contract extension with the Rams in the offseason, so they’ll be happy to target him at high tempo in the 2021 NFL Kickoff Game. Buffalo might have a better offense than Los Angeles, but these Fantasy points are split between multiple players. Kupp has less target competition on his offense, especially after Robert Woods was dealt to Tennessee in the offseason.
Part of McClure’s optimal NFL DFS strategy also includes lining up Bills quarterback Josh Allen. Buffalo’s signalman has been extremely consistent over the past two seasons. In fact, Allen has consecutive years of at least 4,400 passing yards and 36 touchdowns, and he has at least 420 rushing yards and six rushing touchdowns every year of his career.
Additionally, 10 of the 11 starters slated for Buffalo’s offense are returning players from last year, so continuity should lead to big numbers for Allen. His ability to impact the game in various ways is a big reason McClure is so high on Allen against the Rams on Thursday night. See the rest of McClure’s NFL DFS player pool here.
How to Set NFL DFS Lineups for Bills vs Rams
McClure is also targeting an undervalued player who is expected to explode in numbers in the 2022 NFL Kickoff Game. That pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here.
So who does Mike McClure put in his optimal NFL DFS rosters for the 2022 NFL Kickoff Game? Visit SportsLine now to see the NFL DFS picks, rankings, tips and optimal stacks, all from a daily fantasy expert with nearly $2 million in earnings, and find out.