After leading 17-7 late in the third quarter, the Los Angeles Rams scored 13 unanswered points to earn a 20-17 win over the San Francisco 49ers in last year’s NFC Championship Game. These two teams will meet for the first time since that title game on Monday Night Football, and many NFL Fantasy Daily players are hoping for a repeat of Matthew Stafford’s performance. The eventual Super Bowl champion quarterback threw for 337 yards and two touchdowns in this contest and could be a popular option in the NFL DFS squad.
However, Stafford has thrown a league-leading five interceptions in the first three weeks of the season, which could create at least cause for concern when filling your NFL DFS lineups. What stars can you count on for Monday Night Football and what is the most effective NFL DFS strategy for the Rams against the 49ers? Before you make your NFL DFS picks for 49ers vs. Rams, be sure to check out the NFL DFS tips, strategy and player projections from SportsLine Fantasy daily expert Mike McClure.
McClure is a legendary DFS professional player with over $2 million in career earnings. His methodology has led to huge wins on FanDuel and DraftKings. He won two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top 10s in tournaments with over 130,000 entrants on DraftKings. His rosters have also finished in the top 1% in over a dozen other tournaments.
It uses a powerful prediction model that simulates every instant NFL action, taking into account factors such as games, statistical trends, and injuries. This allows him to find the best DFS values which he only shares with SportsLine members.
In Week 3, McClure had Eagles quarterback Jalen Hurts as one of his top NFL DFS picks for FanDuel and DraftKings: The Result: Hurts had 340 passing yards, 20 rushing yards and three touchdowns passing, returning 30.6 points on DraftKings and 27.6 points on FanDuel. Everyone who had it in their lineups was on course for a huge day.
Now, McClure has turned his attention to the Rams vs. 49ers and locked in his top fantasy football daily picks. You can only see his picks and analysis on SportsLine.
Top NFL DFS picks for Rams vs. 49ers
One of McClure’s top NFL DFS picks for Monday Night Football is 49ers wide receiver Deebo Samuel. Perhaps the NFL’s most versatile offensive weapon, Samuel put up staggering numbers a season ago, catching 77 passes for 1,405 yards and six scores while rushing 59 times for 365 yards and eight more touchdowns.
So far in 2022, he’s carried the ball 17 times for 111 yards and a touchdown while catching 12 passes for 131 yards. In his last four meetings against the Rams, including the NFC Championship Game, Samuel has 24 catches for 397 yards and two scores while rushing for 107 yards and two other scores.
McClure’s optimal NFL DFS strategy also includes lining up Rams wide receiver Cooper Kupp. After a season in which he caught 145 passes for 1,947 yards and 16 touchdowns, Kupp is once again posting sensational numbers. He caught 28 passes for 280 yards and three touchdowns and had a 20-yard rushing touchdown last week against the Cardinals.
Kupp was targeted 35 times in the first three weeks of the season to lead the league and also has the highest target share (34.7%) and instant share (98.3%) of all receivers in the league. NFL. He had 11 catches for 142 yards and two touchdowns in the NFC title game win over San Francisco last season and has passed the 100-yard mark in his last three games against the 49ers. You can see the rest of McClure’s NFL DFS tips here.
How to Create NFL DFS Lineups for the 49ers vs. the Rams
McClure is also targeting another undervalued option that could explode in numbers. This choice could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of McClure’s NFL DFS picks, on SportsLine.
Who does Mike McClure include in his NFL DFS Optimal Lineups for Monday Night Football? And which under-the-radar player is a must-have? Visit SportsLine now to see the NFL DFS picks, rankings, tips and optimal stacks, all from a DFS expert who has made millions with his daily fantasy picks, and find out.