The combination was also found to be “ at least as good ” as green-lipped mussel oil for reducing markers of muscle damage and pain after eccentric exercise, according to results published in the Journal of Food Supplements.
“To our knowledge, this is the first study to date that has demonstrated the effectiveness of combining a mixture of green-lipped mussel oil and New Zealand krill to mitigate indirect causes. muscle damage and inflammation after eccentric exercise “, Wrote the researchers.
The combined product included Pharmalink International’s PCSO-524 oil (Lyprinol / Omega-XL) derived from New Zealand green-lipped mussel (Perna canaliculus) And Antarctic krill oil (Euphausia superba) In a ratio of 75% to 25%. Hong Kong-based Pharmalink International funded the study.
Researchers at Indiana University recruited 51 untrained men to participate in their randomized, double-blind, parallel group study. The men were randomly assigned to consume 600 mg / d of PCSO-524 or the mussel-krill oil combination (designated ESPO-572) for 26 days, then suffered a descent bout. The supplementation continued for an additional 72 hours.
The results showed that the interventions produced similar results in reducing the increase in delayed-onset muscle pain (DOMS) 24, 48, and 72 hours after exercise, while both also provided joint protection at 48 and 72. hours.
However, the consumption of the combined product led to a significantly greater range of motion than that of the PCSO-524 group.
Mechanisms of action
Commenting on the potential mechanisms of action to explain the superiority of the combined product for range of motion, the researchers noted that krill oil contains astaxanthin (an antioxidant) and unique phospholipids, including phosphatidylcholine, phosphatidylserine and phosphatidic acid, which can stimulate muscle recovery by facilitating muscle protein synthesis.
“Our data supports the use of ESPO-572, a new nutraceutical, to reduce the deleterious effects of [exercise-induced muscle damage] in untrained men, ” Wrote the researchers.
“Although the data from the present study is encouraging, future surveys using ESPO-572 to reduce [exercise-induced muscle damage] and inflammation has to consider various other demographics such as trained athletes and the elderly ”. They concluded.
Source: Dietary Supplement Journal
Published online ahead of print, doi: 10.1080 / 19390211.2020.1853649
“Effectiveness of a Combined New Zealand Green-Lipped Mussel and Antarctic Krill Oil Supplement on Markers of Exercise-Induced Muscle Damage and Inflammation in Untrained Men”
Authors: MJ Barenie,