The PGA and LPGA Tours have formed a new 32-man mixed team event with a $4m (£3.3m) prize fund.
The first Grant Thornton Invitational will feature 16 players from each tour and will take place December 8-10 in Florida.
It will be the first time in 24 years that the Tours have held an annual tournament for both male and female players.
LPGA commissioner Mollie Marcoux Samaan said it was a “significant step forward” for golf.
“We couldn’t be more thrilled to add the Grant Thornton Invitational to our 2023 schedule,” she added.
“By joining forces with the PGA Tour to organize a mixed event where the best male and female golfers in the world compete, we will provide a memorable and entertaining experience for all golf fans, showcasing the incredible skills of our players in a new context to a new audience.
“This is a significant step forward for golf, women’s golf and the LPGA.”
The tournament will be organized by the Tiburon Golf Club and the Ritz-Carlton Naples.