Colts vs. Steelers odds, spread, line: Monday Night Football picks, NFL predictions from advanced model

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The teams on the sidelines of the NFL playoff picture will face off on Monday Night Football when the Pittsburgh Steelers meet the Indianapolis Colts. The Steelers (3-7), trying to avoid their first losing record in two decades, have had just six losing seasons since 1971. The Colts (4-6-1), who have only made the playoffs playoffs only twice in the past seven years, have not finished below third place in the AFC South standings since 2011. Pittsburgh has won the last seven regular season meetings between the teams, and every team has gone 1-1 directly the last two games.

Kickoff from Lucas Oil Stadium in Indianapolis is scheduled for 8:15 p.m. ET. Indianapolis is a 2.5-point favorite in Caesars Sportsbook’s latest Colts vs. Steelers odds, while the over/under for total runs scored is 39.5. Before you lock in any Steelers vs Colts picks or NFL bets, you should check out the SportsLine Projection Model NFL Predictions.

The model, which simulates every NFL game 10,000 times, has grown more than $7,000 for players to $100 on top NFL picks since its inception. The model enters Week 12 of the 2022 NFL season on an incredible 155-109 run on NFL’s top picks that dates back to the 2017 season.

The model has also ranked in the top 10 on NFLPickWatch four of the last six years on NFL direct picks and has beaten more than 94% of CBS Sports Football Pick’em players four times during that time. Anyone who followed him is upstairs.

Now the model has broken down the Colts vs. Steelers on MNF. You can head over to SportsLine to see the choices. Here are the NFL lines and trends for Steelers vs. Colts:

  • Spread Colts vs Steelers: Indianapolis -2.5
  • Colts vs. Steelers over/under: 39.5 points
  • Colts vs. Steelers silver line: Steelers +118, Colts -140
  • PIT: Steelers are 6-2 ATS in their last eight games after a loss to the ATS
  • IND: Colts are 7-3 ATS in last 10 games after back-to-back loss
  • Colts vs. Steelers: See the picks on SportsLine

Featured game | Indianapolis Colts vs. Pittsburgh Steelers

Why the Colts can cover

Quarterback Matt Ryan completed 23 of 32 attempts (71.9%) for 213 yards last week against Philadelphia and will go for his third straight game without an interception. Ryan has seven touchdowns with one interception and a 104.2 rating in four home starts this season. He’s had 350 or more passing yards in two of his last three home starts and is aiming for his third straight start against Pittsburgh with 285 or more passing yards and a 95-plus rating. Ryan has seven touchdowns with zero interception and a 107.1 rating in his last four starts against opponents AFC North. He also has six touchdowns and no interceptions in his last five Monday Night Football starts.

Running back Jonathan Taylor rushed for 84 yards and his third touchdown of the season last week. He’s looking for his third straight game with 90 or more scrimmage yards and a rushing TD and has 75 or more scrimmage yards in three of four home games this season. He rushed for 74 yards and two touchdowns last meeting with Pittsburgh and is looking for his sixth consecutive prime-time game with 100 yards from scrimmage or more. See which team to choose here.

Why the Steelers can cover

Despite that, the Colts aren’t a lock to cover the Steelers vs. Colts spread. That’s because rookie quarterback Kenny Pickett has been playing better lately and is coming off a solid outing against the Bengals, completing 25 of 42 attempts for 265 yards and a touchdown. In seven games this season, Pickett has completed 155 of 237 passes (65.4%) for 1,426 yards and three touchdowns. He’s been knocked out eight times, but hasn’t thrown an interception since Oct. 30 in the loss to Philadelphia.

Running back Najee Harris also leads the offense. He leads the team with 148 carries for 550 yards (3.7 average) and three touchdowns. Harris also has 28 receptions for 138 yards (4.9 average) and two scores, converting nine first downs to passing offense. Harris has rushed for 189 yards over the past two games, including 99 in a 20-10 rush against the New Orleans Saints on Nov. 13. Find out which team to choose here.

How to make Colts vs. Steelers picks

The model broke down Monday Night Football’s Steelers vs. Colts game from every angle. He looks at the total, with the model projecting a combined 41 points. It also indicates that one side of the spread hits almost 60% of the time. See who it’s all about at SportsLine.

So who wins the Steelers against the Colts on Monday Night Football? And which side of the spread hits almost 60% of the time? Visit SportsLine now to find out which side of the Steelers vs. Colts spread you should be on everywhere, all of the model on a 155-109 roll on his top-rated NFL picks, and find out.



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