Bills vs Patriots odds, line, spread: Thursday Night Football picks, NFL predictions from proven model

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An AFC East battle features the Buffalo Bills (8-3) visiting the New England Patriots (6-5) on Thursday Night Football. Buffalo heads into this division game on a two-game winning streak. On Thanksgiving Day, the Bills outscored the Detroit Lions 28-25. Meanwhile, New England saw their three-game winning streak snapped, losing 33-26 to the Minnesota Vikings on Thanksgiving night.

Kickoff is scheduled for 8:15 p.m. ET. Buffalo is favored by 4.5 points in Caesars Sportsbook’s latest Bills vs. Patriots odds, and the over/under is 43.5. Before making any Patriots vs. Bills picks, be sure to check out the NFL predictions and SportsLine projection model betting tips.

The model, which simulates every NFL game 10,000 times, has grown more than $7,000 for players to $100 on top NFL picks since its inception. The model enters Week 13 of the 2022 NFL season on an incredible 155-110 run on NFL’s top picks that dates back to the 2017 season.

The model has also ranked in the top 10 on NFLPickWatch four of the last six years on NFL direct picks and has beaten more than 94% of CBS Sports Football Pick’em players four times during that time. Anyone who followed him is upstairs.

Now, the model has set his sights on Bills vs. Patriots and has just locked in his picks and NFL TNF Week 13 predictions. You can visit SportsLine now to see the model choices. Here are the NFL odds and betting lines for Patriots vs Bills:

  • Difference between the Bills and the Patriots: Buffalo -4.5
  • Bills vs. Patriots over/under: 43.5 points
  • Bills vs. Patriots money line: Buffalo -220, New England +180
  • BUF: Bills are 6-2 ATS in last eight games in December
  • NE: Patriots are 4-0 ATS in their last four against AFC opponents
  • Bills vs. Patriots pick: See the picks on SportsLine

Featured Game | New England Patriots vs. Buffalo Bills

Why bills can cover

Buffalo has one of the most explosive and electric offenses in the league. The Bills enter this contest ranked second in total offense (415.9) and scoring (28.1), but third in passing offense (279.2). They are led by quarterback Josh Allen.

Allen is a standout athlete who has one of the strongest throwing arms in the league. He can let it rip 70 yards with ease while possessing pinpoint accuracy. The 2020 Pro Bowl selection is also a superb running threat and will consistently pick up easy yards with his legs. Allen is second in the league in passing yards (3,183), second in passing touchdowns (23) and third in QBR (73.6). Additionally, he leads the team in rushing yards (561) with five rushing scores. See which team to choose here.

Why the Patriots can cover

Bill Belichick will have his team ready to roll in this divisional contest. New England has a solid defense that plays extremely fast and physically. This unit is ranked fourth in total defense (307.8) and ninth in pass defense (198.5) and run defense (109.3).

Linebacker Matt Judon is running a monster campaign. Judon has become a constant threat screaming from the edge with exceptional instincts as a passing thrower. The three-time Pro Bowl selection is explosive off the start and solid against the run. The 30-year-old leads the league in sacks (13) with 11 TFLs. Judon continues to dominate for the Patriots and will be hungry in this prime-time affair. See which team to choose here.

How to make choices between Bills and Patriots

SportsLine’s model looks at total points. In fact, he claims a combined 44 points. It also indicates that one side of the spread hits well over 50% of the time. You can only get the model’s TNF picks from SportsLine.

So who wins the Patriots against the Bills on Thursday Night Football? And which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Patriots vs. Bills spread, all from the advanced model that costs well over $7,000 on its NFL picks, and find out.



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